i even scooped deadspin! here's another surefire winner for you highbrow dandies, care of our truest beacon for shining hope and universal, nondenominational salvation, america's funniest home videos:
12/29/10
12/28/10
Surprise!
The pilot says we're stopping in Chicago for the night. Are you around?
Let's watch the Hawks and drink beer! I'll tell you about the two separate times this month that people have talked to me about how LOTR Dance Party recently reminded them - and people we've never met - how much we controlled high school.
12/25/10
12/22/10
Whose coming with me?
April 7th - April 10th
I'm rounding up some friends (some old, some newish) to partake in a weekend of food and music filled debauchery. See me for details, but know my flight is booked. This is actually happening.
12/21/10
Pass the Damn Treaty
If there was any doubt, this picture should prove that it's probably best not to let these people have nuclear weapons.12/19/10
12/17/10
12/14/10
1-UP
Yes, that was the nerdiest thing ever...maybe this will get me some indie cred:
Horse Feathers - Drain You by GardenGrassCrap
@Josh- Great AIDS post! (srsly)
HIV CURED
for sweet, simple adam: the huffington post
for everyone else:
HIV entry into CD4+ cells requires interaction with a cellular receptor, generally either CCR5 or CXCR4. We have previously reported the case of an HIV-infected patient in whom viral replication remained absent despite discontinuation of antiretroviral therapy after transplantation with CCR5
32/32 stem cells. However, it was expected that the long-lived viral reservoir would lead to HIV rebound and disease progression during the process of immune reconstitution. In the present study, we demonstrate successful reconstitution of CD4+ T cells at the systemic level as well as in the gut mucosal immune system following CCR532/32 stem cell transplantation, while the patient remains without any sign of HIV infection. This was observed although recovered CD4+ T cells contain a high proportion of activated memory CD4+ T cells, i.e. the preferential targets of HIV, and are susceptible to productive infection with CXCR4-tropic HIV. Furthermore, during the process of immune reconstitution, we found evidence for the replacement of long-lived host tissue cells with donor-derived cells indicating that the size of the viral reservoir has been reduced over time. In conclusion, our results strongly suggest that cure of HIV has been achieved in this patient.
for everyone else:
HIV entry into CD4+ cells requires interaction with a cellular receptor, generally either CCR5 or CXCR4. We have previously reported the case of an HIV-infected patient in whom viral replication remained absent despite discontinuation of antiretroviral therapy after transplantation with CCR5
32/32 stem cells. However, it was expected that the long-lived viral reservoir would lead to HIV rebound and disease progression during the process of immune reconstitution. In the present study, we demonstrate successful reconstitution of CD4+ T cells at the systemic level as well as in the gut mucosal immune system following CCR532/32 stem cell transplantation, while the patient remains without any sign of HIV infection. This was observed although recovered CD4+ T cells contain a high proportion of activated memory CD4+ T cells, i.e. the preferential targets of HIV, and are susceptible to productive infection with CXCR4-tropic HIV. Furthermore, during the process of immune reconstitution, we found evidence for the replacement of long-lived host tissue cells with donor-derived cells indicating that the size of the viral reservoir has been reduced over time. In conclusion, our results strongly suggest that cure of HIV has been achieved in this patient.
COOPA'S BACK!!!
Well it looks like my blogger account disappeared on me so I have been out of the loop for a few months now. Thanks to Mitch I'm back on so sorry for being so mia lately. I'll begin with nothing else than the best hockey goal ever...
http://www.youtube.com/watch?v=H3vG3ZTxQ68
Love you all and hope to see a few of you during the christmas holidays!
http://www.youtube.com/watch?v=H3vG3ZTxQ68
Love you all and hope to see a few of you during the christmas holidays!
R. Kelly - A Tribute
R. Kelly on Fallon a couple nights ago showed off a new soultry sultry sound that should make the cut on more than a few background-music-to-boning mix tapes. After seeing it though, it did cause me to reminisce on the legend of Kels--here's just a taste of his greatness....
Oh and if you haven't seen Aziz Ansari's bit on him, check it out now.
12/12/10
12/10/10
Dance moves I'm working on
Besides being awesome, this video has a meaningful story behind it.
And here's a cool way to gush over Girl Talk's creativity.
12/9/10
12/8/10
just pooped me pants
What was our goal for post numbers this year? Because I'm abouta start spamming this thing
12/7/10
12/4/10
"Jesus saves, but Gretzky scores on the rebound."
That one is from Kevin Griffith from Columbus, Ohio. People are writing in to this blog with the best graffiti they've seen.
My second favorite so far: "Hammertime" - on a stop sign
12/3/10
What do...
Roger Moore
Huey Lewis
George Costanza
Ricki Lake
George Wendt
Carlton from the Fresh Prince
The Black Guy from Miami Vice
Theo Huxstable
Glenn Close
Pamela Anderson
Leslie Nielsen
Boyzone
Dolph Lundgren
Kelly McGillis
Daryl Hannah
The Hulk
Roger Dorn
Milli Vanilli
...and many more have in common? They're all in this video...
Huey Lewis
George Costanza
Ricki Lake
George Wendt
Carlton from the Fresh Prince
The Black Guy from Miami Vice
Theo Huxstable
Glenn Close
Pamela Anderson
Leslie Nielsen
Boyzone
Dolph Lundgren
Kelly McGillis
Daryl Hannah
The Hulk
Roger Dorn
Milli Vanilli
...and many more have in common? They're all in this video...
12/2/10
12/1/10
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